Active Funds

Title: Noninvasive Noncontact High-Density Optical Imaging of Neonatal Intraventricular Hemorrhage

Sponsor: NIH/NICHD R01 HD101508-01 04/10/2020-03/31/2025

PI: Guoqiang Yu

Title: Perioperative Diffuse Optical Imaging of Tissue Blood Flow and Oxygenation for Optimization of Mastectomy Skin Flap Viability

Sponsor: NIH/NIBIB R01 EB028792-01 03/15/2020-11/30/2023

PI: Guoqiang Yu

Title: Continuous and Longitudinal Monitoring of Cerebral Blood Flow and Metabolism in Freely Moving Rodents

Sponsor: NIH/NINDS R56 NS117587 09/01/2020-08/31/2021

PI: Guoqiang Yu

Title: Development of a Wearable Fluorescence Imaging Device for Intraoperative Identification of Brain Tumors

Sponsor: NIH/NCI 1R41CA243600-01 08/01/2019-07/31/2021

PI: Guoqiang Yu

Title: Development of a Wearable Fluorescence Imaging Device for Intraoperative Identification of Brain Tumors

Sponsor: Kentucky SBIR/STTR Matching Grant 08/01/2020-06/30/2021

PI: Guoqiang Yu

Title: A Low-cost Compact Diffuse Speckle Contrast Flow-oximeter for Neonatal Brain Monitoring

Sponsor: NIH/NICHD R21HD091118-01A1 02/10/2018-01/31/2021

PI: Guoqiang Yu

Title: A Multiscale Multimodal Diffuse Optical Device for Early Diagnosis of Preclinical Alzheimer’s Disease

Sponsor: NIH/NICHD 3R21HD091118-02S1 09/01/2019-01/31/2021

PI: Guoqiang Yu

Title: Prebiotics Intervention to Reduce Alzheimer's Disease Risk via Brain-Gut Axis in an APOE4 Mouse Model

Sponsor: NIH/NIA RF1AG062480 05/01/2019-02/29/2024

Role: Co-I (Yu, 1 month)

PI: Ai-Ling Lin

Title: Implementing a Novel, Nultimodal Technique for Monitoring Cerebrovascular Hemodynamics in Mice as a Diagnostic and Prognostic Tool for Single and Repeated Mild TBI

Sponsor: NIH/NINDS 1R21NS114771-01A1 06/01/2020-05/31/2022

Role: Co-I (Yu, 0.6 months)

PI: Kathryn Saatman

Title: RII Track 2 FEC: Innovative, Broadly Accessible Tools for Brain Imaging, Decoding, and Modulation

Sponsor: NSF EPSCoR (#1539068) 08/01/2015-12/31/2020

Role: Co-I (Yu, 1 month)

MPIs: Sridhar Sunderam, University of Kentucky; Walt Besio, University of Rhode Island; Lei Ding, University of Oklahoma

Title: University of Kentucky Center for Cancer and Metabolism

Sponsor: NIH COBRE #1P20GM121327-01 03/01/2017-12/31/2021

Role: Co-I (Yu, 0.5 months)

PI: Daret St. Clair

itle:            Spatially Resolved Diffuse Correlation Spectroscopy for Cerebral Blood Flow Monitoring in Mouse Stroke Model
Sponsor:     AHA Grant-In-Aid #16GRNT30820006 07/01/2016-06/30/2018
PI:                Guoqiang Yu

Title:            RII Track 2 FEC: Innovative, Broadly Accessible Tools for Brain Imaging, Decoding, and Modulation
Sponsor:     NSF EPSCoR                                                   08/01/2015-07/31/2019
Role:            Co-I (Yu)
MPIs:           Sridhar Sunderam, University of Kentucky; Walt Besio, University of Rhode Island; Lei Ding, University of Oklahoma

Title:            Intraoperative Imaging of Mastectomy Skin Flap for the Guidance of Breast Reconstruction
Sponsor:     National Endowment for Plastic Surgery Grant 07/01/2017-06/30/2019
Co-PIs:        Lesley Wong, Guoqiang Yu

Title:            Vitamin D Contribution to Muscle Metabolic Function in the Elderly
Sponsor:     NIH R21 AG046762-02                                    08/20/2014-06/30/2018
Role:            Co-I (Yu)PI:                Thomas Travis

Title: Noncontact Diffuse Optical Assessment of Mastectomy Skin Flaps
Sponsor: National Endowment for Plastic Surgery Grant 07/01/2015-06/30/2017
Co-PIs: Lesley Wong, Guoqiang Yu

Title: Diffuse Optical Monitoring of Head and Neck Tumor Therapy
Sponsor: NIH R01 CA149274-01A1 7/1/2010-4/30/2015
PI: Guoqiang Yu
Co-Is: Mahesh Kudrimoti, Scott Stevens, Brent Shelton

Title: Noncontact Diffuse Optical Assessment of Pressure Ulcer and Therapy
Sponsor: NIH R21 AR062356-01 2/15/2012-1/31/2015
PI: Guoqiang Yu
Co-Is: Sara Salles, Karin Swartz

Title: Noninvasive Optical Diagnosis of Cerebrovascular Disease in Older Population
Sponsor: UK Pilot Grant Funding for Studies on Alzheimer’s Disease (AD) 7/1/2013-6/30/2014
PI: Guoqiang Yu
Co-Is: Charles D. Smith, David K. Powell, Gregory A. Jicha, Yang Jiang

Title: Noncontact Diffuse Optical Quantification of Hemodynamic Contrast in Breast Tumor
Sponsor: University of Kentucky (UK) CCTS Pilot Program 2/1/2012-1/31/2014
PI: Guoqiang Yu
Co-Is: Margaret Szabunio, Brent Shelton

Title: Development of Diffuse Optical Spectroscopies for Monitoring Cerebral Blood Flow and Oxygenation in Mouse Stroke Model
Sponsor: AHA Postdoctoral Fellowship 11POST7360020 7/1/2011-6/30/2013
PI: Yu Shang
Mentor: Guoqiang Yu

Title: A Portable Optical Flow-Oximeter for Assessment of Cerebral Hemodynamics and Metabolism during Obstructive Sleep Apnea (OSA)
Sponsor: AHA BGIA 2350015 7/1/2009-6/30/2012
PI: Guoqiang Yu
Co-Is: Don Hayes Jr

Title: Contribution of Altered Muscle Hemodynamics to Fatigability in Older Persons with and without Fibromyalgia
Sponsor: NIH R21 AG034279-01 9/15/2009-8/31/2011
PI: Charlotte Peterson, Leslie Crofford
Co-Is: Guoqiang Yu, Leigh Callahan

Title: Assessment of Muscle Vascular Disease with Diffuse Light
Sponsor: NIH R21 HL083225-01 2/15/2006-1/31/2010
PI: Guoqiang Yu
Co-Is: Arjun Yodh, Turgut Durduran, Thomas Floyd

Title: MRI Susceptometry for Measuring Hemoglobin Saturation In Vivo
Sponsor: NIH R21 HL088182-01A2 4/1/2008-3/31/2010
PI: Felix Wehrli
Co-Is: Guoqiang Yu, Thomas Floyd, Jeremy Magland, Emile Mohler

Title: Diffuse Optical Mapping of Blood Flow, Oxygenation, and Metabolism in Ischemic Skeletal Muscle
Sponsor: AHA BGIA 0665446U 7/1/2006-6/30/2009
PI: Guoqiang Yu
Co-Is: Arjun Yodh, Turgut Durduran, Emile Mohler

Title: Real-time Diffuse Optical Measurement for In-vivo PDT Dosimetry of Human Prostate
Sponsor: DOD W81XWH-04-1-0006 2/1/2004-1/31/2007
PI: Guoqiang Yu
Co-Is: Arjun Yodh, Turgut Durduran, Steven Hahn

Title: Diffuse Light Imaging of Flow, Oxygen & Brain Metabolism
Sponsor: NIH R01 HL077699-01 9/1/2004-8/31/2008
PI: Arjun G. Yodh
Co-Is: Guoqiang Yu, Turgut Durduran, Joel H. Greenberg

Title: Absolute Measurement of Cerebral Blood Flow Using Diffuse Optics
Sponsor: NIH R21 EB007610-01 8/1/2007-7/31/2009
PI: Turgut Durduran
Co-Is: Guoqiang Yu, Arjun Yodh, Joel H. Greenberg, John A. Detre

Title: Real-time Diffuse Optical Measurement for Dosimetry During Photofrin Pleural Photodynamic Therapy
Sponsor: Upenn Abramson Cancer Center 7/1/2005-6/30/2006
PI: Steven Hahn
Co-Is: Guoqiang Yu, Arjun Yodh

Active Funds

Completed Funds

Stanley and Karen Pigman College of Engineering